Hi Matt. Welcome to the forums.
You can use a widescreen tablet with a non wide-screen monitor, but you might find it takes you a while to get used to the difference in aspect.
But you can always re-map the area of the screen to match a sub-portion of the tablet to keep the aspect between the two the same.
By aspect I mean that if you move your hand in a circular motion on the wide-screen tablet, you'd get an oval shape on your display. The Wacom control panel will allow you to re-map the tablet to match the display.
I look forward to seeing what you produce with ArtRage!
AndyRage's mantra for graphics engine code:
"Sure - how hard can it be?"