It's not a 'wear and tear' thing. ArtRage can cause slowdowns on your computer after use in a couple of ways. It creates files for 'undo' in the temp directory. When you quit ArtRage, (or start a new project) they're deleted. Also, after a while the available memory for an application can become fragmented. Quitting and restarting an application usually solves that.
There shouldn't be any permanent changes to your computer from using ArtRage, except lots of painting files with your creations in them, and an improvement to your painting skills.
AndyRage's mantra for graphics engine code:
"Sure - how hard can it be?"